Orodental Local Drug Delivery

Orodental Delivery Systems: an Overview

Oral cavity can be used for local drug delivery as in for periodontitis, dental caries or for oral mucosal drug delivery as for alveolar osteitis, analgesia or transmucosal systemic effect as for smoking cessation or delivery of biotechnological products like proteins and peptides. This article gives an overview of basic structure, function, biochemistry, and permeability of the oral cavity. Di...

Local Drug Delivery

Periodontal diseases are considered infection of the periodontium, because there is bacterial etiology, an immune response, and tissue destruction. Putative pathogens associated with periodontal diseases are susceptible to a variety of antiseptics and antibiotics. Methods employed to convey antimicrobial agents into periodontal pockets have included rinsing, irrigation, systemic administration,...

Local drug delivery in periodontology

Periodontitis describes a group of related inflammatory disease resulting in destruction of the tissues that support the tooth. It results from extension of the inflammatory process initiated in the gingiva to the supporting periodontal tissues. Clinical features of periodontitis include bleeding, pus discharge, halitosis, tooth mobility, functional impairment and ultimately tooth loss. Scaling...

Local Drug Delivery –A Targeted Approach

Successful periodontal treatment is dependent on anti-inflammatory procedure which includes both mechanical and chemotherapeutic approach. Chemotherapeutic approach includes local application or sustained release of local drug delivery agents and systemic approaches. Locally delivered antimicrobial agents are administered to prevent plaque accumulation and to disinfect the root surface and adja...

vancomycin loaded chitosan beads as a drug delivery system for local antibiotic delivery in some infections